Determinants of myocardial perfusion reserve measured from coronary sinus phase-contrast imaging during regadenoson stress CMR

Determinants of myocardial perfusion reserve measured from coronary sinus phase-contrast imaging during regadenoson stress CMR

Background Measurement of myocardial perfusion reserve (MPR) can potentially extend the scope of conventional myocardial perfusion imaging from detection of flow limiting epicardial stenosis to assessment of coronary microvascular function. Recent studies have suggested that MPR may improve risk stratification of patients with known or suspected CAD. MPR has traditionally been measured using PE...

Assessment of global myocardial perfusion reserve using cardiovascular magnetic resonance of coronary sinus flow at 3 Tesla

BACKGROUND Despite increasing clinical use, there is limited data regarding regadenoson in stress perfusion cardiovascular magnetic resonance (CMR). In particular, given its long half-life the optimal stress protocol remains unclear. Although Myocardial Perfusion Reserve (MPR) may provide additive prognostic information, current techniques for its measurement are cumbersome and challenging for ...

Detection of obstructive coronary artery disease using regadenoson stress and 82Rb PET/CT myocardial perfusion imaging.

UNLABELLED Our objective was to study the diagnostic performance of regadenoson (82)Rb myocardial perfusion PET imaging to detect obstructive coronary artery disease (CAD). METHODS We studied 134 patients (mean age, 63 ± 12 y; mean body mass index, 31 ± 9 kg/m(2)) without known CAD (96 with coronary angiography and 38 with low pretest likelihood of CAD). Stress left ventricular ejection fract...

Regadenoson Cardiac Stress Myocardial Perfusion Scintigraphy

LV wall motion assessment during regadenoson vasodilator stress CMR

Background Regadenoson (REG) is a commonly used vasodilator stress agent that causes an increase in sympathetic response with associated increase in myocardial contractility and ventricular function in addition to coronary vasodilation. This agent has demonstrated high accuracy to detect coronary stenosis during myocardial perfusion imaging, but global and regional LV functional changes immedia...